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ako imate porfiriju (nasledni poremećaj metabolizma porfirina, koji se karakteriše stvaranjem plikova po koži, bolovima u stomaku i poremećajima na nivou mozga i nervnog sistema)

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ako ste alergični (preosetljivi) na diazepam, druge benzodiazepine ili na bilo koju pomoćnu supstancu koja ulazi u sastav leka 

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teofilin (za lečenje astme i drugih problema sa disanjem), jer može da ubrza izlučivanje diazepama iz organizma